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  • Title: Is immediate bony microsurgical reconstruction after head and neck tumor ablation associated with a higher rate of local recurrence?
    Author: Hanken H, Wilkens R, Riecke B, Al-Dam A, Tribius S, Kluwe L, Smeets R, Heiland M, Eichhorn W, Gröbe A.
    Journal: J Craniomaxillofac Surg; 2015 Apr; 43(3):373-5. PubMed ID: 25701393.
    Abstract:
    The purpose of this retrospective study was to examine the possible effect of immediate bony microvascular free flap reconstruction of mandibular defects after radical tumor resection of oral squamous cell carcinoma (OSCC) on the rate of local relapse. Our own data regarding recurrence rates for 1-step immediate reconstruction were compared to the published recurrence rates of 2-step reconstructions. A total of 21 patients (aged 45-77 years) with OSCC who underwent a primary surgical therapy with subsequent immediate bony microvascular free flap reconstruction of mandibular defects were followed up for 18-38 months. Four local relapses (19%) were recorded, all in patients with initial tumor stage of T4. Although intraoperative histological findings were R0 in all 21 cases, definitive histology later detected R1 status in the resected bone in 2 cases (10%). Immediate bony free flap reconstruction of mandibular defects after radical surgical resection of OSCC does not seem to increase the risk of local recurrence nor affect patient survival when compared with the 2-step surgical approach.
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