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  • Title: Takayasu arteritis presenting as retinal and vertebrobasilar ischemia.
    Author: Edwards KK, Lindsley HB, Lai CW, Van Veldhuizen PJ.
    Journal: J Rheumatol; 1989 Jul; 16(7):1000-2. PubMed ID: 2570149.
    Abstract:
    A young woman presented with a 4-month history of retinal and vertebrobasilar ischemia. Angiography demonstrated narrowing of major branches of the aortic arch. Intractable, severe retroorbital pain of the right eye developed after a middle cerebral artery stroke. During 4 weeks of aggressive immunosuppressive therapy including IV high dose bolus corticosteroids and pulse cyclophosphamide, her neurologic deficit improved transiently, but her retroorbital pain persisted. She died of staphylococcal sepsis and pneumonia. An autopsy demonstrated thrombotic or fibrous occlusion, with minimal inflammation, of extracranial arteries.
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