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  • Title: Effects of selective and non-selective beta 1-blockade on renin secretion in the isolated rat kidney.
    Author: Haro JM, Vargas F, Castillo MA, García-Torres L, Acuña D.
    Journal: Rev Esp Fisiol; 1989 Jun; 45(2):195-8. PubMed ID: 2570449.
    Abstract:
    The participation of beta 1-adrenoceptor on renin secretion was studied in perfused rat kidney. Administration of propranolol, inhibited the renin release mediated by isoproterenol. Likewise, metoprolol and practolol, showed a similar potency to propranolol in inhibiting isoproterenol-induced renin secretion. These results suggest that the for isoproterenol-induced renin release in rats is a beta 1-type adrenoceptor.
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