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  • Title: Characterization of Atypical Preeclampsia.
    Author: Rojas-Arias JL, Ortiz-López LD, Orduña-Aparicio WJ, Quintero-Loaiza CA, Acuña-Osorio E, Franco-Hernández A, Parra-Saavedra M, Molina-Giraldo S, Figueras F.
    Journal: Fetal Diagn Ther; 2015; 38(2):119-25. PubMed ID: 25721893.
    Abstract:
    OBJECTIVE: To characterize patients with atypical preeclampsia (PE), in relation to socio-demographic characteristics, clinical presentation, maternal complications and perinatal outcome. MATERIALS AND METHODS: Between July 1, 2011 and November 30, 2013, a cohort was created of women attended at a Obstetric High-dependency Unit who met criteria for atypical PE: gestational hypertension with severe hypertension or symptoms or laboratory signs suggestive of microangiopathy/hemolysis; normotensive proteinuria with the presence of symptoms or laboratory signs suggestive of microangiopathy/hemolysis; presence of PE or eclampsia or HELLP syndrome appearing after 48 h postpartum, and, PE or eclampsia appearing before 20 weeks of pregnancy. RESULTS: A total of 200 women fulfilling criteria for atypical PE, were included: 61.5% corresponded to non-proteinuric gestational hypertension, 35.5% to normotensive proteinuria and 3% to PE/eclampsia in late postpartum. Criteria for severe maternal morbidity were present in 12% of the cases and there were no maternal deaths. There were 6 perinatal deaths. CONCLUSION: Atypical preeclampsia is a type of preeclampsia not fully recognized that is associated with maternal and neonatal morbidity, mainly related to smallness-for-gestational-age and low birth weight. Vasospasm symptoms are a key element to detect this condition.
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