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  • Title: Fungus or parasite or both: a diagnostic challenge.
    Author: Panchabhai TS, Bandyopadhyay D, Piliang M, Duggal A.
    Journal: J Glob Infect Dis; 2015; 7(1):40-2. PubMed ID: 25722621.
    Abstract:
    Protothecosis is a rare opportunistic infection caused by achlorophilic algae Prototheca wickerhamii, mainly in immunocompromised hosts. Due to their morphologic appearance in routine culture media, they can often mimic yeast-like opportunistic pathogens such as Pneumocystis jirovecii. This can delay the identification of other culprit organisms. We present a fatal case of protothecosis in a 74-year-old immunosuppressed male with concomitant Pneumocystis jirovecii pneumonia (PJP). The presence of a coinfection along with resemblance in routine culture media and microbiological and histopathological staining can prove to be a diagnostic challenge and delay appropriate care of an immunosuppressed patient.
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