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  • Title: Should the Cytobrush be used in routine screening for cervical pathology?
    Author: van Erp EJ, Dersjant-Roorda MC, Arentz NP, Stijnen T, Trimbos JB.
    Journal: Int J Gynaecol Obstet; 1989 Oct; 30(2):139-44. PubMed ID: 2572484.
    Abstract:
    In 632 women visiting a family planning clinic, paired cervical smears were taken using a wooden spatula and a Cytobrush. Of the spatula smears 7.8% were unreliable with too little or scanty material to allow a cytologic diagnosis (class 0); 17.7% of spatula smears were inadequate, lacking endocervical cells. Combined spatula/Cytobrush cytology reduced these figures significantly; 4.3% unreliable smears and 3.2% inadequate specimens. Seventy-three (11.6%) of the smears revealed some abnormality, in most cases Papanicolaou class IIIA, suggestive of mild dysplasia. In 10 cases, dysplastic cells were found only in the Cytobrush cytology. It is concluded that the Cytobrush adds to the improvement of smear quality and the accuracy of routine cervical cytology obtained by relatively inexperienced smear takers.
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