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  • Title: Antihypertensive drugs: adverse reactions and metabolic effects in elderly patients.
    Author: Gifford RW.
    Journal: Geriatrics; 1989 Oct; 44 Suppl B():37-43. PubMed ID: 2572514.
    Abstract:
    Symptomatic and metabolic side effects seen in the treatment of elderly hypertensive patients are an area of concern for physicians. Of the four drug classes used as Step 1 antihypertensive agents--diuretics, beta-blockers, ACE inhibitors, and calcium-entry blocking agents--only diuretics have been studied as monotherapy for the elderly in placebo-controlled, long-term clinical trials. These studies have shown diuretics to be well tolerated in this patient population, producing only mild, infrequent side effects.
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