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  • Title: Synthesis of 3-bromosubstituted pyrroles via palladium-catalyzed intermolecular oxidative cyclization of bromoalkynes with N-allylamines.
    Author: Zheng J, Huang L, Li Z, Wu W, Li J, Jiang H.
    Journal: Chem Commun (Camb); 2015 Apr 07; 51(27):5894-7. PubMed ID: 25729782.
    Abstract:
    This paper describes a novel palladium-catalyzed oxidative cyclization of bromoalkynes with N-allylamines via cascade formation of C-N and C-C bonds. During this process, the bromine atom was retained to form 3-bromo-pyrroles, which can undergo the subsequent structural modifications.
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