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  • Title: [A case of long-term survival in a patient with rectal cancer with virchow lymph node metastasis, liver metastases, and lung metastases].
    Author: Oyanagi H, Kameyama H, Nogami H, Shimada Y, Nakano M, Nakano M, Ishikawa T, Sakata J, Kobayashi T, Minagawa M, Kosugi S, Koyama Y, Wakai T.
    Journal: Gan To Kagaku Ryoho; 2014 Nov; 41(12):1674-6. PubMed ID: 25731292.
    Abstract:
    A 69-year-old man with advanced rectal cancer and liver metastases was treated with 2 courses of chemotherapy with irinotecan and S-1 followed by low anterior resection and partial hepatectomy. Chemotherapy with S-1 was then administered for 22 months. However, lung metastases developed, for which partial pneumonectomy was performed. Seven months later, computed tomography (CT) revealed swelling of the left supraclavicular lymph node. Despite chemotherapy with 5- fluorouracil, Leucovorin, and oxaliplatin (mFOLFOX6); 5-fluorouracil, Leucovorin and irinotecan (FOLFIRI); and capecitabine plus bevacizumab, the lung metastases recurred and Virchow lymph node swelling was noted again. Accordingly, palliative therapy was administered. The patient died 3 years 1 month after Virchow lymph node resection. Herein, we describe a case of advanced rectal cancer, in which lung and Virchow lymph node metastases developed after liver metastasis. Surgical excision of the metastases resulted in long-term survival of 6 years following the first operation.
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