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  • Title: A coumarin lignanoid from the stems of Kadsura heteroclita.
    Author: Su W, Zhao J, Yang M, Yan HW, Pang T, Chen SH, Huang HY, Zhang SH, Ma XC, Guo DA, Khan IA, Wang W.
    Journal: Bioorg Med Chem Lett; 2015 Apr 01; 25(7):1506-8. PubMed ID: 25736995.
    Abstract:
    Coumarinlignan (1), possessing a unique coumarin-containing lignan skeleton, was isolated from the stems of Kadsura heteroclita. Its structure and absolute configuration were determined by spectroscopic techniques, especially 2D NMR and X-ray crystallographic data analyses. The proposed biosynthetic pathway is discussed. This new compound showed good anti-HBV activity against HBeAg and HBsAg, and moderate anti-fibrotic and neuroprotective activities.
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