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  • Title: Thyroxine-induced metamorphosis in the axolotl (Ambystoma mexicanum).
    Author: Coots PS, Seifert AW.
    Journal: Methods Mol Biol; 2015; 1290():141-5. PubMed ID: 25740483.
    Abstract:
    The axolotl (Ambystoma mexicanum) has remained an important model for regeneration and developmental biology for over a century. Although axolotls in captive-bred colonies usually exist in an aquatic form, they retain the ability to undergo metamorphosis following exposure to thyroid hormone. Here we present a robust method for inducing metamorphosis in adult axolotls that results in high survivability and produces terrestrial animals that can be maintained in long-term captivity.
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