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  • Title: Evidence of unilateral metastatic pulmonary calcification with a prolonged Fever and arthralgia caused by acute lymphoblastic leukemia in a chronic dialysis patient.
    Author: Saraya T, Sada M, Ohkuma K, Sakuma S, Tsujimoto N, Yoshida S, Fujiwara M, Tsukahara Y, Kurai D, Ishii H, Takizawa H, Goto H.
    Journal: Intern Med; 2015; 54(1):63-7. PubMed ID: 25742896.
    Abstract:
    A 55-year-old man was transferred to our hospital with unilateral lung lesions, a persistent fever and vague chest pain with arthralgia lasting for three months. He had been treated for end-stage renal disease with hemodialysis for 15 years and had a medical history of recurrent subcutaneous calciphylaxis due to secondary hyperparathyroidism. Transbronchial biopsied specimens demonstrated metastatic pulmonary calcification, and a bone marrow biopsy showed Philadelphia chromosome-positive acute lymphoblastic leukemia. Although metastatic calcification often lacks specific symptoms, the lungs is a primary site for deposition. This is the first report of unilateral metastatic pulmonary calcification associated with secondary hyperparathyroidism.
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