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  • Title: Lack of association between scleroderma and types I and III procollagen gene restriction fragment length polymorphisms.
    Author: Kratz LE, Boughman JA, Needleman BW.
    Journal: Arthritis Rheum; 1989 Dec; 32(12):1597-600. PubMed ID: 2574578.
    Abstract:
    Restriction fragment length polymorphisms (RFLPs) in types I and III procollagen genes were studied in 62 scleroderma patients and 138 healthy controls. Allelic frequencies were determined for each RFLP, and comparisons were made between the 2 populations, stratifying them by race when appropriate. No statistically significant differences were observed for the frequencies of any of the RFLPs studied.
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