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Title: The association of serotype and pulsed-field gel electrophoresis genotype in isolates of Streptococcus pneumoniae isolated in Israel. Author: Bar-Meir M, Naaman G, Assous M, Korenman Z, Valinsky L, Picard E. Journal: Int J Infect Dis; 2015 May; 34():38-40. PubMed ID: 25749648. Abstract: The relationship between Streptococcus pneumoniae isolates causing invasive infections in children admitted to a single center in central Israel was examined by pulsed-field gel electrophoresis (PFGE) and serotyping. Although there was a close correlation between serotype and PFGE clone, the genetic diversity varied by serotype, with some genotypes comprising multiple serotypes. Additionally, clones C and D were associated with higher penicillin minimum inhibitory concentrations. Serotyping alone may be insufficient for epidemiological mapping of pneumococcal isolates in the era of pneumococcal conjugate polysaccharide vaccines.[Abstract] [Full Text] [Related] [New Search]