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  • Title: Incidence of nodal metastasis and isolated aortic metastases in patients with surgically staged endometrioid endometrial cancer.
    Author: Sautua RR, Goiri K, Calle MA, Marin IJ, Artola AL.
    Journal: Int J Gynecol Cancer; 2015 Jun; 25(5):875-8. PubMed ID: 25774712.
    Abstract:
    OBJECTIVES: To describe the incidence of lymph node metastasis in patients with surgically staged endometrioid-type endometrial cancer in Donostia University Hospital and evaluate the presence of isolated aortic metastasis. METHODS: Using a prospectively maintained database, we recorded all cases of endometrioid endometrial cancer that underwent lymph node dissection and determined the rate and location (pelvic or para-aortic) of lymph node metastasis. RESULTS: A total of 212 patients with endometrioid type endometrial cancer were surgically treated at our institution from May 2008 to June 2013. Ninety underwent pelvic and para-aortic lymphadenectomy. Thirteen had positive nodes upon pathological examination. Six (6.6%) of 90 patients had positive para-aortic nodes with negative pelvic nodes. CONCLUSIONS: In our series, the incidence of isolated aortic nodal metastasis is high compared with other published reports. Performing aortic lymphadenectomy only in case of positive pelvic nodes would have underdiagnosed 6 (46%) of 13 stage IIIC cancers.
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