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  • Title: [Reasoning of the usage of multimicroelement drugs and monophytodrugs in complex treatment of patients with chronic atrophic gastritis].
    Author: Molodovets' OB, Pozur NZ, Havrysh TIu, Chaplyns'ka NV, Zozuliak NV, Iurak MZ, Kulaiets' VM.
    Journal: Wiad Lek; 2014; 67(2 Pt 2):359-61. PubMed ID: 25796870.
    Abstract:
    It was investigeted 126 patients with chronic atrophic gastritis, aged 19-73 years. Chronic inflammatory and degenerative processes of the gastric mucosa contributed to the destabilization of cell membranes. We found that patients with chronicatrophic gastritis have disturbances of lipid peroxidation and antioxidant defense, which is manifested by the accumulation of products of peroxidation and decreased activity of enzymes of antioxidant defense. Activation of lipid peroxidation, accompanied by increased levels of proinflammatory cytokines and deficiency of essential trace elements imbalance contributes antioxidant defense. After using basic therapy, it was no certain normalization of lipid peroxidation, antioxidant defense and restoration of microelement homeostasis in patients with chronic atrophic gastritis, which served as the justification for the development and testing of methods of treatment with the purpose of regulation of these processes.
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