These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The distribution of substance P, enkephalin, and serotonin immunoreactivities in the area postrema of the rat and cat.
    Author: Newton BW, Maley B, Traurig H.
    Journal: J Comp Neurol; 1985 Apr 01; 234(1):87-104. PubMed ID: 2579986.
    Abstract:
    With the use of the peroxidase-antiperoxidase technique the distribution of substance P (SP), enkephalin (ENK), and serotonin (5HT) immunoreactivities were described in the area postrema of the rat and cat. In both species, immunoreactivity in the area postrema was differentially distributed as either fibers only, or cell bodies and fibers. In the rat and cat, ENK had the greatest accumulation of immunoreactive fibers, followed by 5HT and SP. In the area postrema of the rat the majority of SP-, ENK-, and 5HT-immunoreactive fibers were along the ventral and ventrolateral borders, with fewer immunostained fibers at the dorsal surface. The area postrema of the cat had the majority of SP-, ENK-, and 5HT-immunoreactive fibers at the ventral and lateral borders, with fewer immunostained fibers at the dorsal and medial borders. In both species, the area postrema's central region contained the fewest immunostained fibers. In general, for each putative neurotransmitter examined, immunostained fibers in both species progressively decreased in number rostrocaudally. Serotonin- and ENK-immunoreactive cell bodies were found in the rat area postrema; in the cat area postrema only ENK-immunoreactive cell bodies were present. The area postrema of both species lacked SP-immunoreactive cell bodies. The heterogeneous distribution of immunoreactive fibers and cell bodies within the area postrema of the rat and cat may reflect the different functions of the area postrema in both species.
    [Abstract] [Full Text] [Related] [New Search]