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  • Title: Maternal glucose during pregnancy and after delivery in women with gestational diabetes mellitus on overweight status of their children.
    Author: Zhang S, Liu H, Zhang C, Wang L, Li N, Leng J, Li Y, Liu G, Fan X, Yu Z, Yang X, Baccarelli AA, Hou L, Hu G.
    Journal: Biomed Res Int; 2015; 2015():543038. PubMed ID: 25802854.
    Abstract:
    OBJECTIVE: To examine the association of maternal glycemia during pregnancy and after delivery with anthropometry in the offspring of mothers with gestational diabetes mellitus (GDM). METHODS: A total of 1,263 GDM mothers and their children finished the health survey at 1-5 years after delivery. RESULTS: Offspring of GDM mothers who were diagnosed with diabetes during pregnancy had higher prevalence of overweight, higher mean weight for height Z scores, and higher mean BMI for age Z scores at 1-5 years old than the offspring of GDM mothers who were diagnosed with impaired glucose tolerance (IGT) during pregnancy. Offspring of GDM mothers who developed diabetes 1-5 years after delivery had higher mean values of Z scores for weight for height and BMI for age at 1-5 years old than the offspring of GDM mothers who had normal glucose or prediabetes after delivery. CONCLUSIONS: Offspring of GDM mothers who were diagnosed with diabetes during pregnancy or after delivery had an increased risk of childhood overweight or weight gain at 1-5 years old compared with children of GDM mothers with IGT during pregnancy or with normal glucose or prediabetes after delivery.
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