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  • Title: [Changes in the substance P content of the blood and hypothalamus during experimental emotional stress].
    Author: Iumatov EA, Poppai M, Ratsak R.
    Journal: Biull Eksp Biol Med; 1985 Apr; 99(4):397-9. PubMed ID: 2580575.
    Abstract:
    A study was made of the content of substance P in the blood and hypothalamus of Wistar rat brain in acute and chronic emotional stress and after intraperitoneal injection of substance P in a dose of 250 mg/kg. A possibility was demonstrated of inducing long-term changes in the content of substance P in the hypothalamus after a single injection. Exposure to a single 24-hour stress was followed by an increase in the substance P content in the hypothalamus.
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