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  • Title: [In vitro study of bone marrow from leukemia patients and patients without hematologic disease].
    Author: Varga G, Borbényi Z, Krizsa F, Cserháti I.
    Journal: Folia Haematol Int Mag Klin Morphol Blutforsch; 1985; 112(1):125-33. PubMed ID: 2581857.
    Abstract:
    The bone-marrow of 26 patients not affected with hematological diseases and 10 patients with untreated leukemia was investigated according to Dexter in long-term cultures. Survival time and cell content of those long-term cultures started with normal bone marrow were not influenced significantly, if reinoculation was made with autologeneic or allogeneic bone marrow. Even without repeated inoculation, leukemic cells grew for a longer time in long-term cultures than normal bone marrow cells. As far as the outcome of the disease is concerned, no conclusion can be drawn from the duration of cultivating leukemic cells growth.
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