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  • Title: Effects of intravenously administered 6-hydroxydopamine on the content of monoamines in the median eminence and neurointermediate lobe of the rat.
    Author: Sheward WJ, Watts AG, Fink G, Smith GC.
    Journal: Neurosci Lett; 1985 Apr 09; 55(2):141-4. PubMed ID: 2582316.
    Abstract:
    The effects of intravenous administration of 6-hydroxydopamine (6-OHDA) on the content of catecholamines in the median eminence and neurointermediate lobe was studied in male rats. The results confirmed previous findings of a depletion of catecholamines in both regions as a result of this lesion, although the magnitude of the effect was less than that revealed by fluorescence histochemistry. Administration of desipramine before 6-OHDA injection produced a more specific lesion, depleting dopamine but leaving noradrenaline unaffected.
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