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  • Title: Synthesis and antibacterial evaluation of some teicoplanin pseudoaglycon derivatives containing alkyl- and arylthiosubstituted maleimides.
    Author: Csávás M, Miskovics A, Szűcs Z, Rőth E, Nagy ZL, Bereczki I, Herczeg M, Batta G, Nemes-Nikodém É, Ostorházi E, Rozgonyi F, Borbás A, Herczegh P.
    Journal: J Antibiot (Tokyo); 2015 Sep; 68(9):579-85. PubMed ID: 25829202.
    Abstract:
    Bis-alkylthio maleimido derivatives have been prepared from teicoplanin pseudoaglycon by reaction of its primary amino group with N-ethoxycarbonyl bis-alkylthiomaleimides. Some of the new derivatives displayed excellent antibacterial activity against resistant bacteria.
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