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  • Title: A route to the heterocyclic cluster of the E-series of thiopeptide antibiotics.
    Author: Hwang HJ, Ciufolini MA.
    Journal: J Org Chem; 2015 Apr 17; 80(8):4184-8. PubMed ID: 25836570.
    Abstract:
    A concise route to the 3-hydroxypyridine core of thiopeptide antibiotics such as nocathiacin is described. Key phases of the sequence involve a modified Hantzsch pyridine construction and a chemoselective Peng deprotection of a phenolic MOM ether.
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