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  • Title: Relationship between Cardio-Ankle Vascular Index (CAVI) and Obstructive Sleep Apnea (OSA).
    Author: Romsaiyut S, Chotnaiyawattrakul W, Boonyasirinant T.
    Journal: J Med Assoc Thai; 2015 Feb; 98(2):156-62. PubMed ID: 25842796.
    Abstract:
    BACKGROUND AND OBJECTIVE: A non-invasive test called Cardio-Ankle Vascular Index (CA VI) measures aortic stiffness, which is an early sign of atherosclerosis. Obstructive sleep apnea (OSA) has a close association with cardiovascular mortality and morbidity. We sought to assess the relationship between OSA and arterial stiffness. MATERIAL AND METHOD: Seventy-one patients with OSA (apnea-hypopnea index AHI ≥ 5, mean age 51.5 ± 14.1 years, 27 females) and 11 controls (AHI < 5, mean age 56.8 ± 11.8 years, 5 females) were enrolled in the study. In all subjects, arterial stiffness (CAVI) was performed and recorded along with blood pressure, pulse pressure of brachial arteries, and ankle arteries. RESULTS: The demographic data of the patients with OSA and controls were not significantly different. Subjects with OSA demonstrated higher values ofmean ankle artery pulse pressure than the controls (73.1 ± 14.6 vs. 59.6 ± 6.1 mmHg, respectively), but arterial stiffness and CAVI had no statistically significant difference (7.47 ± 1.68 vs. 7.25 ± 1.61, respectively). CONCLUSION: There was no relationship between arterial stiffness CAVI, and the presence of OSA. However; there was a significant association between ankle artery pulse pressure and the presence of OSA.
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