These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Guanine tetrads: an IRMPD spectroscopy, energy resolved SORI-CID, and computational study of M(9-ethylguanine)(4)(+) (M = Li, Na, K, Rb, Cs) in the gas phase.
    Author: Azargun M, Fridgen TD.
    Journal: Phys Chem Chem Phys; 2015 Oct 21; 17(39):25778-85. PubMed ID: 25845669.
    Abstract:
    The intrinsic properties of the alkali metal cationized G-tetrads, M(9eG)4(+) (M = Li, Na, K, Rb, Cs) composed of 9-ethylguanine (9eG), were studied by a combination of mass spectrometric techniques. The gas phase structures were probed by infrared multiple photon dissociation (IRMPD) spectroscopy in both the fingerprint region (900-1850 cm(-1)) and the N-H/C-H stretching region (2700-3800 cm(-1)). The gas phase structures were found to be similar for all five complexes and most consistent with the metal-centred G-tetrad structure. Energy-resolved CID was also used to compare the gas phase stabilities of the G-tetrads and showed that Na(9eG)4(+) was more stable than Li(9eG)4(+) followed by the K(+), Rb(+), and Cs(+) G-tetrads in order. The experimental energy ordering was reproduced by electronic structure calculations of the energies. Furthermore, the computations also showed that the lower stability to loss of 9-ethylguanine for the Li(+) complex could be due to a strong destabilization of the neutral G-tetrad due to the persistence toward maximizing the ion-dipole interactions while also maintaining hydrogen bonding interactions.
    [Abstract] [Full Text] [Related] [New Search]