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  • Title: Protein synthesis in muscles from normal and dystrophic hamsters.
    Author: Saleem M, Nicholls DM.
    Journal: Biochem J; 1979 Apr 15; 180(1):51-8. PubMed ID: 258600.
    Abstract:
    Homogenates of hindleg muscle were obtained from control and dystrophic male hamsters, 30 and 190 days of age, and were used to prepare the postmicrosomal pH5-supernatant fraction. The activity of this fraction in the incorporation of [14C]phenylalanyl-tRNA into peptides was increased in the dystrophic-muscle preparations. No such increase was found in brain or liver preparations from dystrophic hamsters. The increased capacity for aminoacyl-tRNA binding that was observed in preparations from dystrophic animals is discussed.
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