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  • Title: Weight loss in a patient with polycystic kidney disease: when liver cysts are no longer innocent bystanders.
    Author: Cecere N, Hakem S, Demoulin N, Hubert C, Jabbour N, Goffette P, Pirson Y, Morelle J.
    Journal: Acta Clin Belg; 2015 Oct; 70(5):369-71. PubMed ID: 25866379.
    Abstract:
    OBJECTIVE AND IMPORTANCE: Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent inherited kidney disorder, and liver involvement represents one of its major extra-renal manifestations. Although asymptomatic in most patients, polycystic liver disease (PLD) can lead to organ compression, severe disability and even become life-threatening, thereby warranting early recognition and appropriate management. CLINICAL PRESENTATION: We report the case of a 56-year-old woman with ADPKD and severe weight loss secondary to a giant hepatic cyst compressing the pylorus. Partial hepatectomy was required after failure of cyst aspiration and sclerotherapy, and patient's condition improved rapidly. DISCUSSION AND CONCLUSIONS: We discuss the presentation and classification of compressing liver cysts, and the available therapeutic alternatives for this potentially severe complication of ADPKD.
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