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  • Title: Experience with continuous enteral levodopa infusions in the treatment of 9 patients with advanced Parkinson's disease.
    Author: Sage JI, Trooskin S, Sonsalla PK, Heikkila RE.
    Journal: Neurology; 1989 Nov; 39(11 Suppl 2):60-3; discussion 72-3. PubMed ID: 2586763.
    Abstract:
    Nine patients with advanced Parkinson's disease were started on continuous enteral levodopa infusions during the past 3 years. Six have remained on the infusion system for 1 to 28 months. All patients experienced immediate amelioration of motor fluctuations, and 5 patients continue to obtain relief. One patient found that his ability to achieve the "on" state without unacceptable dyskinesia waned. Experience thus far indicates that continuous long-term levodopa infusions are a practical but complex form of therapy for patients failing more conventional treatment.
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