These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: High Familial Correlation in Methylphenidate Response and Side Effect Profile.
    Author: Gazer-Snitovsky M, Brand-Gothelf A, Dubnov-Raz G, Weizman A, Gothelf D.
    Journal: J Atten Disord; 2019 Jan; 23(2):135-139. PubMed ID: 25899797.
    Abstract:
    OBJECTIVE: To examine whether a familial tendency exists in clinical response to methylphenidate. METHOD: Nineteen pairs of siblings or parent-child stimulant-naive individuals with ADHD were prescribed methylphenidate-immediate release, and were comprehensively evaluated at baseline, Week 2, and Week 4, using the ADHD Rating Scale IV, Clinical Global Impression Scale, and the Barkley Side Effects Rating Scale. RESULTS: We found significant intraclass correlations in family member response to methylphenidate-immediate release and side effect profile, including emotional symptoms and loss of appetite and weight. CONCLUSION: Family history of response to methylphenidate should be taken into account when treating ADHD.
    [Abstract] [Full Text] [Related] [New Search]