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  • Title: Parenteral pentazocine and diabetes mellitus: a double whammy for cutaneous complication.
    Author: Phaujdar S, Sarkar RN, Bhattacharyya K.
    Journal: J Assoc Physicians India; 2014 Oct; 62(10):52-4. PubMed ID: 25906524.
    Abstract:
    Pentazocine, a non-narcotic analgesic, though has no addictive potential but abused frequently via parenteral route for its psychological dependence. It causes local sclerosis resulting in non-healing ulcer at injection sites. Diabetes mellitus suppress host immunity, making them vulnerable to various bacterial skin and soft tissue infection among which mkethicillin resistant staphylococcus aureus (MRSA) infection are predominant. We report a case, a 50-year-old shopkeeper who used to inject pentazocine primarily as analgesic, later became addicted to it. Blindly injecting the drug in any approachable soft tissue resulted in woody induration of local skin with multiple ulcers in his both arms. He later developed type 2 Diabetes mellitus which made the scenario even worser.
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