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  • Title: Gentle blood aspiration and tube cushioning reduce pneumatic tube system interference in lactate dehydrogenase assays.
    Author: Strubi-Vuillaume I, Carlier V, Obeuf C, Vasseur F, Maury JC, Maboudou P, Mangalaboyi J, Durocher A, Launay D, Noel C, Brousseau T.
    Journal: Ann Clin Biochem; 2016 Mar; 53(Pt 2):295-7. PubMed ID: 25911571.
    Abstract:
    BACKGROUND: Use of a hospital pneumatic tube system may be associated with measurement errors. METHODS: A venous blood sample was collected from 79 patients into a pair of lithium heparin tubes; one tube was sent to the laboratory by porter and the other was sent via the pneumatic tube system. Plasma lactate dehydrogenase concentrations were then assayed. RESULTS: Lactate dehydrogenase concentrations were overestimated (median bias: 18.8%) when evacuated vacuum lithium heparin tubes were sent by pneumatic tube system. This bias was reduced by bubble-wrapping the standard lithium heparin tube or using Monovette lithium heparin tubes in aspiration mode (median bias: +8.7% and -0.3%, respectively). CONCLUSIONS: Cushioning and aspiration-mode sampling may limit pneumatic tube system-associated overestimation of lactate dehydrogenase concentrations.
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