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  • Title: Congenital intrinsic duodenal obstruction: problems in the diagnosis and management.
    Author: al-Salem AH, Khwaja S, Grant C, Dawodu A.
    Journal: J Pediatr Surg; 1989 Dec; 24(12):1247-9. PubMed ID: 2593054.
    Abstract:
    Nineteen infants with intrinsic duodenal obstruction are analyzed. Atresia was the most common lesion. An exceptionally high rate of associated anomalies (73.7%) were present; Down's syndrome, the single most common anomaly, was seen in 47% of the infants. In seven infants, the diagnosis was delayed and in another three it was made intraoperatively while establishing a gastrostomy for esophageal atresia. Three infants died without operation because of gross prematurity and multiple anomalies. Of the 16 operated on, three died, one due to peritonitis and the other two because of metabolic derangements. Of the various operative procedures used, no significant difference was found in the final outcome of treatment. A schematic approach to the diagnosis and management is proposed.
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