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  • Title: Bioactivity of cellulose acetate/hydroxyapatite nanoparticle composite fiber by an electro-spinning process.
    Author: Kwak DH, Lee EJ, Kim DJ.
    Journal: J Nanosci Nanotechnol; 2014 Nov; 14(11):8464-71. PubMed ID: 25958547.
    Abstract:
    Hydroxyapatite/cellulose acetate composite webs were fabricated by an electro-spinning process. This electro-spinning process makes it possible to fabricate complex three-dimensional shapes. Nano fibrous web consisting of cellulose acetate and hydroxyapatite was produced from their mixture solution by using an electro-spinning process under high voltage. The surface of the electro-spun fiber was modified by a plasma and alkaline solution in order to increase its bioactivity. The structure, morphology and properties of the electro-spun fibers were investigated and an in-vitro bioactivity test was evaluated in simulated body fluid (SBF). Bioactivity of the electro-spun web was enhanced with the filler concentration and surface treatment. The surface changes of electro-spun fibers modified by plasma and alkaline solution were investigated by FT-IR (Fourier Transform Infrared Spectroscopy) and XPS (X-ray Photoelectron Spectroscopy).
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