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  • Title: [Age-related peculiarities of thymus reaction to the exposure to helium-neon laser and injured muscle alloplasty with the muscle tissue from the animals of the same age].
    Author: Bulyakova NV, Azarova VS.
    Journal: Morfologiia; 2015; 147(1):26-35. PubMed ID: 25958725.
    Abstract:
    Histological, cytological and morphometric changes in the thymus of 1 month-old, adult (3-4 months-old) and old (24-30 months-old) rats (24 animals in each group) were studied during muscle regeneration after the alloplasty of the injured area with the muscle tissue from the animal of the same age. Muscles of the donor or recipient were subjected to the course of preliminary irradiation with He-Ne laser (dose: 4.5-5.4 J/cm2 for each extremity; total dose of 9.0-10.8 J/cm2 per animal). It was shown that the exposure of gastrocnemius muscles that were prepared for the operation to He-Ne laser radiation decreased morpho-functional activity of the thymus in young, adult and old recipient rats the before surgery. This was demonstrated by its weaker reaction to the allograft during the early time intervals after surgery. The observed effect was more pronounced with the increasing age of an animal.
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