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  • Title: Comparison of amine fluoride and chlorhexidine mouth rinses in the control of plaque and gingivitis--a randomized controlled clinical trial.
    Author: Priya BM, Galgali SR.
    Journal: Indian J Dent Res; 2015; 26(1):57-62. PubMed ID: 25961617.
    Abstract:
    OBJECTIVES: The objective of this triple blind randomized controlled clinical trial was to compare the efficacy of a mouth rinse containing amine fluoride (AmF) and chlorhexidine in controlling the supragingival plaque accumulation and gingival inflammation during a 4-week period in patients with chronic gingivitis. SUBJECTS AND METHODS: A total of 30 patients were participated in this study. Fifteen patients were prescribed an AmF-containing mouth rinse and 15 were prescribed a chlorhexidine mouth rinse. Plaque index, gingival index, bleeding index, tooth stain, and tongue stain (TS) were recorded at baseline, 15 days and 1-month. Patients' perception of odor, taste and any discomfort were recorded. RESULTS: The comparisons between the groups were done using Mann-Whitney U-test. The comparison within the group at different time visits were done using Wilcoxon signed rank test. Both the mouth rinses resulted in a significant decrease in plaque index, gingival index, bleeding index. However, AmF mouth rinse resulted in a statistically significant decrease in bleeding index and gingival index compared to chlorhexidine group. There was no significant difference in tooth stain and TS in both the groups. CONCLUSIONS: The 4 weeks use of AmF containing mouth rinse is effective in reducing the gingival inflammation and plaque.
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