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  • Title: A biochemical study of glycosaminoglycans in the palatal rugae of the monkey (Macaca fascicularis).
    Author: Okazaki J, Gonda Y, Nishiura M.
    Journal: Arch Oral Biol; 1989; 34(7):585-6. PubMed ID: 2597049.
    Abstract:
    Glycosaminoglycans (GAG) were extracted from the connective tissue of the palatal rugae, separated by electrophoresis and compared with the results obtained for the remaining palatal mucosal and gingival connective tissues. The GAG content of the rugae (3.01 mg/g defatted dry weight) was higher than in the remaining palatal mucosa (2.33 mg/g defatted dry weight) or gingiva (1.68 mg/g defatted dry weight). Dermatan sulphate was the predominant GAG in both the palatal rugae (48% of total GAG) and the remaining palatal mucosa (50%) followed by hyaluronic acid (33 and 31% respectively). The results do not support previous histochemical observations in which the rugae appeared to be rich in hyaluronic acid.
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