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  • Title: Three decomposition products of valepotriates from Valeriana jatamansi and their cytotoxic activity.
    Author: Lin S, Chen T, Fu P, Ye J, Yang XW, Shan L, Li HL, Liu RH, Shen YH, Xu XK, Zhang WD.
    Journal: J Asian Nat Prod Res; 2015 May; 17(5):455-61. PubMed ID: 25971678.
    Abstract:
    Three new decomposition products of valepotriates, valtrals A-C (1-3), and two known products, baldrinal and homobaldrinal, are formed during the isolation procedure of the ethanol extract of the whole plants of Valeriana jatamansi. Their structures were determined by spectroscopic methods including IR, MS, 1D, and 2D NMR experiments. Compounds 1-3 showed selective cytotoxicity against metastatic prostate cancer (PC-3M) and colon cancer (HCT-8) cell lines.
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