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  • Title: The biased reptation model of DNA gel electrophoresis: mobility vs molecular size and gel concentration.
    Author: Slater GW, Noolandi J.
    Journal: Biopolymers; 1989 Oct; 28(10):1781-91. PubMed ID: 2597731.
    Abstract:
    The biased reptation model provides a good framework for interpreting the results of continuous field DNA electrophoresis experiments performed in agarose gels. Here we discuss the main features of the mobility-molecular size and mobility-gel concentration diagrams as obtained from new extensive computer simulations of the model. Our aim is to suggest a global and coherent picture of this widely used yet poorly understood experimental technique, and to point out the areas where a systematic experimental study is still needed.
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