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  • Title: The increase in tumor oxygenation under carbogen breathing induces a decrease in the uptake of [(18)F]-fluoro-deoxy-glucose.
    Author: Neveu MA, Bol V, Bol A, Bouzin C, Grégoire V, Feron O, Jordan BF, Gallez B.
    Journal: Radiother Oncol; 2015 Sep; 116(3):400-3. PubMed ID: 25981053.
    Abstract:
    We investigated the impact of oxygenation status (measured by EPR oximetry) on the uptake of (18)F-FDG (measured by PET) in two different tumor models during a carbogen breathing challenge. We observed a significant drop in (18)F-FDG uptake under carbogen breathing that suggests a rapid metabolic adaptation to the oxygen environment.
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