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  • Title: The relation between platelet-to-lymphocyte ratio and Pulmonary Embolism Severity Index in acute pulmonary embolism.
    Author: Kundi H, Balun A, Cicekcioglu H, Cetin M, Kiziltunc E, Cetin ZG, Mansuroglu C, Ornek E.
    Journal: Heart Lung; 2015; 44(4):340-3. PubMed ID: 25998993.
    Abstract:
    PURPOSE: In this study, we aimed to investigate the value of the platelet-to-lymphocyte ratio (PLR) for predicting disease severity based on simplified Pulmonary Embolism Severity Index (sPESI), as well as in-hospital mortality in patients with acute pulmonary embolism (APE). MATERIALS AND METHODS: Our hospital's electronic patient database was searched for the patients with ICD-9 code I26, and eligible 646 patients were included in the study. RESULTS: Univariate logistic regression analysis showed that PLR, pulmonary artery systolic pressure, right ventricular dysfunction, D-dimer level, and white blood cell, lymphocyte, platelet and neutrophil counts were significantly correlated with a high sPESI score in patients with APE. CONCLUSIONS: To the best of our knowledge, this is the first study in the literature showing that a high PLR is independently associated with a high risk of mortality in patients with APE.
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