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  • Title: [Cytoprotective effect of rosaprostol during treatment with non-steroidal anti-inflammatory agents in arthrorheumatic pathologies].
    Author: Cataldo MG, Sallì L, Scalici G, D'Aiuto A, Bongiorno A, Salerno L.
    Journal: Minerva Dietol Gastroenterol; 1989; 35(3):191-4. PubMed ID: 2601868.
    Abstract:
    A clinico-endoscopic study has been carried out in a group of 22 patients treated with 1 g of naproxene + 2 g of rosaprostol compared in a blind situation with another group of 19 patients treated with a similar dose of naproxene + placebo in order to evaluate the cytoprotective action of rosaprostol. Analysis of the results showed a high correlation between intake of rosaprostol and low onset of algico-dyspeptic disturbances and mucosal lesions of some gravity, although the problem of the monitoring of patients undergoing long-term treatment with NSAID remains unsolved.
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