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  • Title: Gender differences between the effect of monosodium glutamate on food intake in rats.
    Author: Racotta R, Hernandez-Garcia A.
    Journal: Physiol Behav; 1989 Aug; 46(2):331-2. PubMed ID: 2602476.
    Abstract:
    Monosodium glutamate (MSG) was recently reported to increase feeding in ad lib. fed rats [Reddy et al.(4)]. In the present study the responses of male and female adult rats to subcutaneous (SC) administration of MSG were compared. In female rats MSG 3 g/kg did not significantly affect food or water intake as compared with SC NaCl 0.9%; MSG 6 g/kg significantly reduced food intake but increased water intake. On the contrary, in male rats MSG 6 g/kg significantly increased food and water intake. It is concluded that there are differences between genders of rats in what concerns the effect of glutamate on food intake.
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