These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Oleanane-type triterpene saponins with collagen synthesis-promoting activity from the flowers of Bellis perennis.
    Author: Morikawa T, Ninomiya K, Takamori Y, Nishida E, Yasue M, Hayakawa T, Muraoka O, Li X, Nakamura S, Yoshikawa M, Matsuda H.
    Journal: Phytochemistry; 2015 Aug; 116():203-212. PubMed ID: 26028520.
    Abstract:
    The methanol extract from Bellis perennis (Asteraceae) flowers was found to promote collagen synthesis in normal human dermal fibroblasts (NHDFs). Seven oleanane-type triterpene saponins, perennisosides XIII-XIX, and two known saponins, bellissaponins BS5 and BS9, were isolated from the methanol extract. The structures were determined based on chemical and physicochemical data, and confirmed using previously isolated related compounds as references. Among the isolates, including 19 previously reported saponins, perennisosides XVIII, I, II, VII, IX, and XI, asterbatanoside D, bernardioside B2, and bellissaponins BS5 and BS9 significantly promoted collagen synthesis at 3-30μM without cytotoxicity.
    [Abstract] [Full Text] [Related] [New Search]