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  • Title: The hollow skull: a sign of brain death in Tc-99m HM-PAO brain scintigraphy.
    Author: Abdel-Dayem HM, Bahar RH, Sigurdsson GH, Sadek S, Olivecrona H, Ali AM.
    Journal: Clin Nucl Med; 1989 Dec; 14(12):912-6. PubMed ID: 2605849.
    Abstract:
    The advantage of Tc-99m HM-PAO, a newly introduced compound for brain perfusion imaging, is illustrated in three patients with suspicion of brain death. With Tc-99m HM-PAO, the carotid flow study is not essential, as it is in the Tc-99m pertechnetate carotid angiogram; planar images are equally useful; and there is no need for SPECT images. For the diagnosis of brain death, Tc-99m HM-PAO can be injected in the intensive care unit and planar images can be obtained at a later time using a mobile camera or whenever the patient can be moved to the nuclear medicine department.
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