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  • Title: Recent advances in research of natural and synthetic bioactive quinolines.
    Author: Chung PY, Bian ZX, Pun HY, Chan D, Chan AS, Chui CH, Tang JC, Lam KH.
    Journal: Future Med Chem; 2015; 7(7):947-67. PubMed ID: 26061110.
    Abstract:
    Many natural products that consist of quinoline core are found to be bioactive and the versatility of quinoline and its derivatives have attracted great attention in the field of drug development. As a result, in recent years, many green and sustainable synthetic approaches for the synthesis of structurally diverse quinolines have been developed. This review covers four main aspects, namely bioactive quinoline alkaloids, the biological activity and mechanism of action of quinoline-based compounds as well as various quinoline syntheses.
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