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  • Title: Aerosol Medications for Treatment of Mucus Clearance Disorders.
    Author: Rubin BK.
    Journal: Respir Care; 2015 Jun; 60(6):825-9; discussion 830-32. PubMed ID: 26070577.
    Abstract:
    Airway mucus hypersecretion and secretion retention can result from inflammation, irritation, stimulation, or mucus-producing tumors. Secretion clearance can be furthered hampered by ciliary dysfunction and by weakness or restrictive lung disease, leading to an ineffective cough. There are a number of different mucoactive medications that have been used to reduce hypersecretion, make secretions easier to transport, or increase the efficiency of cough or mucus clearance. In this paper, I review the pathophysiology of secretory hyper-responsiveness and mucus hypersecretion and discuss the different aerosol medications that can be used to augment secretion clearance.
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