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  • Title: A cross-sectional study of antenatal depressive symptoms in women at high risk for gestational diabetes mellitus.
    Author: Engberg E, Stach-Lempinen B, Sahrakorpi N, Rönö K, Roine RP, Kautiainen H, Eriksson JG, Koivusalo SB.
    Journal: J Psychosom Res; 2015 Dec; 79(6):646-50. PubMed ID: 26073219.
    Abstract:
    OBJECTIVE: To examine differences in antenatal depressive symptoms between women at high risk for gestational diabetes mellitus (GDM) and pregnant women in the general population. METHODS: We recruited pregnant women at high risk for GDM, based on a history of GDM and/or prepregnancy BMI ≥ 30 kg/m(2), (n = 482) and pregnant women in the general population (n = 358) before 20 weeks of gestation. Depressive symptoms were assessed by the Edinburgh Postnatal Depression Scale (EPDS). RESULTS: Of the women at high risk for GDM, 17% had an EPDS score ≥ 10 (indicating risk for depression) compared to 11% of the pregnant women in the general population (p = .025). The mean EPDS score was also higher in the women at risk for GDM (5.5, SD 4.5 vs. 4.6, SD 3.9, p = .004, effect size 0.21 [95% CI: 0.07 to 0.34]). After adjusting for age, prepregnancy BMI and income, the difference between the groups was no longer significant either in the proportion of women having an EPDS score ≥ 10 (p = .59) or in the mean EPDS score (p=.39). CONCLUSION: After controlling for age, prepregnancy BMI and income, women at high risk for GDM did not have greater depressive symptoms compared to pregnant women in the general population in early pregnancy.
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