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  • Title: IBD: Indication extrapolation for anti-TNF biosimilars.
    Author: Vande Casteele N, Sandborn WJ.
    Journal: Nat Rev Gastroenterol Hepatol; 2015 Jul; 12(7):373-4. PubMed ID: 26077557.
    Abstract:
    Biosimilar monoclonal antibodies (mAbs) to TNF are being developed that are highly similar, but not identical to the innovator molecules. CT-P13, a biosimilar of infliximab, is the first anti-TNF mAb to get approval in South Korea, Europe and Canada. However, uncertainties remain about indication extrapolation and interchangeability.
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