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  • Title: Synthesis of dinucleoside phosphorodithioates from nucleoside phosphonodithioates.
    Author: Porritt GM, Reese CB.
    Journal: Nucleic Acids Symp Ser; 1989; (21):55-6. PubMed ID: 2608477.
    Abstract:
    The conversion, in good yield, of 5'-O-(9-phenylxanthen-9-yl) thymidine (1) into the triethylammonium salt of its 3'-phosphonodithioate (2a) is described. The latter compound (2a) is converted into a dinucleoside phosphonothioate (4a), and thence into a corresponding dinucleoside phosphorodithioate (6a) and phosphorothioate (6;X = 0).
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