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  • Title: Host Range Restriction of Epstein-Barr Virus and Related Lymphocryptoviruses.
    Author: Mühe J, Wang F.
    Journal: J Virol; 2015 Sep; 89(17):9133-6. PubMed ID: 26085168.
    Abstract:
    Epstein-Barr-related herpesviruses, or lymphocryptoviruses (LCV), naturally infect humans and nonhuman primates (NHP), but their host range is not well characterized. Using LCV and B cells from multiple species of Hominidae and Cercopithecidae, we show that LCV can immortalize B cells from some nonnative species but that growth transformation is restricted to B cells from their own family of hominoids or Old World NHP, suggesting a high degree of LCV adaptation to their natural primate host.
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